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The human body requires oxygen to survive, and when oxygen levels drop too low, it can lead to serious health problems or even death. While the exact level at which oxygen deprivation becomes life-threatening can vary depending on a number of factors, such as age and overall health, in general, a blood oxygen level of 80 mmHg or below is considered cause for concern. If oxygen levels drop to 60 mmHg or lower, it can be life-threatening, and immediate medical attention is necessary to prevent serious injury or death. It is important to seek medical attention to see how low can your oxygen level go before you die, such as shortness of breath or confusion.